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Scientists Find 33 Genetic Markers In Marijuana That Can Be Targeted To Breed New ‘Enhanced’ Strains ‘Tailored For Medical And Recreational Uses’

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Scientists report that they’ve identified 33 “significant markers” in the cannabis genome that “significantly influence cannabinoid production”—a finding they say promises to drive the development of new plant varieties with specific cannabinoid profiles.

The new article, published last month in the journal The Plant Genome, says the results “offer valuable guidance for Cannabis breeding programs, enabling the use of precise genetic markers to select and refine promising Cannabis varieties.”

“This approach promises to speed up the breeding process, reduce costs significantly compared to traditional methods, and ensure that the resulting Cannabis varieties are optimized for specific medical and recreational needs,” authors wrote, calling the study “a significant stride toward fully integrating Cannabis into modern agricultural practices and genetic research, paving the way for future innovations.”

The analysis involved use of “a high-density genotyping approach” looking at thousands of molecular markers across the genome of 174 cannabis specimens in Canada, each with known levels of cannabinoids such as THCA, CBDA and CBN.

“Using suitable statistical methods,” the team said, “we identified 33 molecular markers associated with 11 cannabinoid traits, most of them having a high impact on the phenotype.”

Among the findings were what the paper calls a “massive” set of genes on one plant chromosome that involved about 60 megabases (Mb) and was associated specifically with THC-dominant cannabis strains.

Authors—from Université Laval in Québec, Canada—said the research represents a shift away from years of cannabis prohibition that “have impeded the establishment of genetic resource collections and the development of advanced breeding practices, thus limiting both the genetic improvement and the understanding of Cannabis traits.”

“These molecular markers will be highly valuable in breeding programs aiming to create new Cannabis variety with enhanced and specific cannabinoid profiles tailored for medical and recreational uses.”

The markers uncovered in the new study “will constitute an essential tool in breeding programs,” the report says, and “promise to accelerate the selection process for promising accessions, potential crossing parents, while significantly reducing costs associated with labor-intensive phenotype-based selection methods.”

The new findings come on the heels of a recent announcement by researchers in South Korea that they successfully identified a new cannabinoid—cannabielsoxa—as well as a number of other compounds “reported for the first time from the flowers of C. sativa.”

Published in the journal Pharmaceuticals, that paper says researchers used chromatographic techniques to isolate the compounds. They also examined their molecular structures and used a metabolic testing method to assess their toxicity to certain cancer cells.

“This study successfully isolated a new cannabinoid and six known cannabinoid compounds, along with a new chlorin-type compound and three additional chlorine-type compounds,” the study said, “which were reported for the first time from the flowers of C. sativa.”

The new cannbinoid, cannabielsoxa, was not among the compounds that researchers identified as potentially toxic to neuroblastoma cells, however.

Other research, published by the American Chemical Society in 2023, identified “previously undiscovered cannabis compounds” that challenged conventional wisdom of what really gives cannabis varieties their unique olfactory profiles.

While research into marijuana has exploded in recent years as the result of more jurisdictions legalizing the drug for medical and adult use, it’s unclear how the Trump administration’s priorities will impact that trend.

For example, under the new administration, “marijuana” is also now one of nearly two dozen “controversial or high-profile topics” that staff and researchers at the National Cancer Institute (NCI) are required to clear with higher-ups before writing about.

A recently leaked agency memo put marijuana and opioids on a list along with vaccines, COVID-19, fluoride, measles, abortion, autism, diversity and gender ideology and other issues that are believed to be personal priorities of Health and Human Services Secretary Robert F. Kennedy Jr. and President Trump.

NCI is part of the National Institutes of Health (NIH), which itself is part of the Department of Health and Human Services (HHS).

Prior to publishing anything on the specified topics, NCI staff are required to send the materials to an agency clearance team, the memo said..

“Depending on the nature of the information, additional review and clearance by the NCI director, deputy directors, NIH, and HHS may be required,” it advised staff. “In some cases, the material will not need further review, but the NCI Clearance Team will share it with NCI leadership, NIH, and/or HHS for their awareness.”

Is Marijuana’s ‘Entourage Effect’ A Real Thing Or Is It Just Marketing Hype?

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Marijuana Users Are Nearly 5 Times As Likely To Regularly Exercise Than Eat Fast Food, Stereotype-Busting Survey Shows

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Marijuana consumers are more than three times more likely to regularly exercise than drink alcohol—and they’re nearly five times more likely to routinely work out than eat fast food—according to another stereotype-defying survey.

The poll from the cannabis telehealth platform NuggMD looked at the habits of cannabis users, who were asked about the frequency they engage in seven different activities—from alcohol consumption to movie theater attendance.

One of the takeaways was that marijuana consumers reported regularly engaging in exercise (27.4 percent daily and 34.9 percent multiple times per week) significantly more often than using alcohol (6.1 percent daily and 11.3 percent multiple times per week).

Another finding from the survey was that cannabis consumers are 4.8 times more likely to regularly exercise than to eat fast food (1.5 percent daily and 11.5 percent multiple times per week).

“This finding is yet more evidence that today’s cannabis consumers defy the prohibitionist stereotype of layabouts munching Doritos and then crossfading with booze to get their fix,” Andrew Graham, head of communications at NuggMD, told Marijuana Moment.

“The data shows that cannabis consumers self-report several healthy lifestyle habits. When compared with federal data on exercise and fast food consumption, our poll shows that cannabis consumers are in fact more likely to exercise and less likely to eat fast food than the average U.S. adult,” he said. “Previous polling we’ve done shows cannabis has a distinct replacement effect on alcohol use, and this poll charts a similar direction.”

“For millions of wellness-focused Americans, cannabis is simply part of the routine. It’s kind of mind-blowing how wrong the prohibitionist crowd is about everything,” Graham said.

Several other studies have similarly found that cannabis users exercise at average or above-average levels compared to non-users, bucking the long-held stigma that marijuana makes people lazy. This is one of the latest data points to show the same.

Notably, the new poll also found that relatively few marijuana consumers frequently use food delivery services, with just 3.3 percent reporting that they order delivery daily and 8.3 percent saying they use such services multiple times a week.

Via NuggMD.

In contrast, 69.5 percent of respondents said they drink coffee regularly. Only 4.5 percent said they often visit movie theaters. And 64.8 percent said they routinely take nutritional supplements.

The survey from NuggMD involved interviews with 603 cannabis consumers, with a +/- 4 percentage point margin of error.

Meanwhile, last year a study found that marijuana consumption prior to exercise can lead to greater enjoyment and an enhanced “runner’s high.”

Another study published in 2023 surveyed 49 runners and found that participants experienced “less negative affect, greater feelings of positive affect, tranquility, enjoyment, and dissociation, and more runner’s high symptoms during their cannabis (vs. non-cannabis) runs.” Participants did run 31 seconds slower per mile when using marijuana, but researchers said that was not statistically significant.

The positive effects of cannabis that the runners reported is consistent with the findings of a 2019 study, which found that people who use marijuana to elevate their workout tend to get a healthier amount of exercise.

Older people who consume cannabis are also more likely to engage in physical activity, according to another study that was published in 2020.

Similarly, in another stereotype-busting study that was published in 2021, researchers found that frequent marijuana consumers are actually more likely to be physically active compared to their non-using counterparts.

Marijuana Dispensary Offers Free Joints For Pics Of Bigfoot Following Local Sighting

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Alcohol And Cannabis Consumer Behavior Evolving

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Their is a new wave of behavior around drinking in public which could have a major impact on the alcohol and cannabis industry.

In bars across the country, a subtle shift is underway: younger patrons, especially Gen Z and Zillennials, are increasingly saying no thanks to opening a tab. It’s not about being antisocial—it’s about financial control, digital habits, and a shifting relationship with nightlife. The younger generation is increasingly turning away from alcohol. A portion are favoring marijuana for relaxation and socializing. Health consciousness, mental wellness, and shifting cultural norms drive this trend. 

RELATED: Mixed Messages From The Feds About Cannabis

Unlike older generations who were more comfortable running a tab and settling up at the end of the night, Gen Z and Zillennials are hyper-aware of where their money is going in real-time. Growing up in the aftermath of the 2008 financial crisis and amid rising costs of living, this generation approaches spending with caution. Mobile banking, budgeting apps, and real-time transaction alerts have made them more vigilant. Opening a bar tab? That’s an invitation to overspend.

Changing Jobs And Thinking Of Cannabis

There’s also the trust factor. Horror stories of mystery charges, lost credit cards, or bars adding gratuities without consent have circulated widely on TikTok and Reddit. Many in this demographic prefer to pay per drink or use digital wallets like Apple Pay or Venmo, minimizing risk and maximizing transparency.

Technology plays a role too. While bar tabs require handing over a physical credit card—something that feels outdated to a smartphone-native generation—Gen Z prefers the immediacy and security of tapping a phone or using a QR code. Bars that still rely on old-school POS systems may seem out of step.

RELATED: Cannabis Is Way Better And Safer Than A Honey Pack

Culturally, going out doesn’t necessarily mean bingeing at a bar anymore. Many younger adults are opting for sober-curious lifestyles or limiting alcohol consumption, and when they do drink, they prefer to keep things low-key and affordable. Also, they see xannabis is seen as a safer, more mindful alternative, aligning with their preference for personalized, low-risk experiences over traditional, high-impact substances like alcohol.

For bar owners, this trend is a wake-up call. Offering easy, transparent, and tech-forward payment options—like mobile ordering and contactless checkout—can help retain Gen Z patrons. Those who resist these shifts risk alienating a generation that values financial autonomy over tradition.

The bottom line? For Gen Z and Zillennials, closing out a tab one drink at a time isn’t just practical—it’s personal.



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Ohio Raises Cannabis Purchasing Limit

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Cannabis shoppers in Ohio can now purchase up to two and a half ounces of cannabis flower from licensed dispensaries under a rule change announced last week by the Division of Cannabis Control (DCC).

Previously, cannabis purchases were capped at a single ounce for flower to prevent product shortages during the adult-use industry’s launch last year.

“Since non-medical cannabis sales began in August 2024, the market has demonstrated the ability to support both medical marijuana patients and non-medical consumers alike,” the agency wrote in a guidance published last week.

The rule change took effect immediately on Wednesday, but while the purchasing limits for cannabis flower products have increased, the regulations on other cannabis products remain unchanged. Outside of cannabis flower, Ohio state law sets a 15,000mb total THC cap on adult-use cannabis purchases — dispensaries are expected to honor the limit by tallying up the total THC content being bought by consumers, including cannabis concentrates, edibles, beverages, and vaporizers.

Licensed cannabis dispensaries in Ohio conducted nearly $400 million in adult-use sales during the first seven months of the legal market.

In March, lawmakers were accused of withholding more than $10 million in adult-use cannabis tax revenue that was supposed to be earmarked for local governments that had opted to allow cannabis businesses.

Meanwhile, Republican lawmakers have more recently been pushing to scale back the state’s voter-approved cannabis legalization law through at least two different proposals: one to cap THC limits in cannabis concentrates and impose other limits that were left out of the voter-approved bill, and one to cut back on the number of home grow plants allowed under state law.

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