magic mushrooms
Psilocybin Mushrooms Enhance Psychological Flexibility, Pilot Study Shows
Published
7 months agoon
The active ingredient in psilocybin mushrooms is being explored for its power to break out of the grip of rigid mental patterns—patterns which often lead to treatment-resistant disorders. Researchers believe it could help to transform therapy by providing an alternative way to tackle mental disorders.
A recent pilot study published in the Journal of Psychedelic Studies has found preliminary evidence that psilocybin, when administered in a group retreat setting, can enhance psychological flexibility. Psychological flexibility means being present in the moment and having the ability to respond to stimuli in ways that serve your values.
The study, “A pilot study of the effect of group-administered psilocybin on psychological flexibility and outcomes,” was conducted by Brian Pilecki, Jason Luoma, and Kati M. Lear.
“I think group-based psilocybin administration is under-studied and has significant value in producing therapeutic change. I also am interested in using psychological flexibility as a way to understand how psychedelics exert their effects and lead to improvements in health and well-being,” study author Brian Pilecki of Portland Psychotherapy told PsyPost.
Nine participants—six female and three male—attended the retreat, ages ranging from 41 to 68. Nine participants were employed: four full-time and five part-time. Four participants endorsed having a regular meditation practice while five did not.
Researchers collected data using a series of assessments at three intervals: one week before the retreat, two weeks after the retreat, and six months later. These assessments utilized standardized questionnaires to measure psychological flexibility, cognitive fusion, values-driven behavior, self-compassion, emotional expressivity, and general well-being.
When asked what their highest dose psilocybin session taken during the retreat was, participants reported between five and 12 grams of dried, homogenized mushrooms, meaning that all participants had at least one “heroic” psilocybin session with a dose that was at least 5 grams.
The study narrowed down quantifiable changes in psychological flexibility rather than just recording any changes in psychological flexibility.
“This study is significant in that it is the first to quantitatively document changes in psychological flexibility facets after psychedelic experiences rather than only more general changes in psychological flexibility,” the study states. “Understanding processes of change involved in psychedelic-assisted therapy is important in informing how psychotherapy can support psychedelic experiences. For example, it might be possible to take steps during preparation to make it even more likely that people will experience cognitive defusion or values clarification during dosing sessions. Alternately, techniques based on psychological flexibility theory might be used to support changes in values that begin during dosing and translate these into long-term behavior change. We are just beginning to understand the link between psychedelics and psychological flexibility and hope this pilot study will spur future research on the topic.”
Psilocybin’s Efficacy to Decrease Cognitive Fusion of Rigid Thought Patterns
The data shows a substantial decrease in cognitive fusion—referring to the grip of rigid thoughts that alter behavior. This drop was significant at the two-week follow-up and persisted through the six-month evaluation, suggesting that participants were able to detach from their thoughts more effectively, allowing them to act more in line with their values rather than being prisoners shaped by habitual thought patterns.
Participants reported improvements in how freely they were able to live according to their values. This was evident from drops in “values obstruction” at both the two-week and six-month follow-up periods. Additionally, there was an increase in values progression by the six-month mark, indicating sustained improvements in the participants’ ability to engage in behaviors that align with their personal values over time.
Researchers also observed increases in self-compassion at both follow-up points, as well as changes in emotional expressivity.
“Our study supported that psilocybin taken in a retreat context can be helpful in enhancing key aspects of psychological flexibility including cognitive defusion, valued living, and self-compassion,” Pilecki told PsyPost. “These improvements suggest that client’s were able to take greater perspective on their thoughts and align their behaviors more closely with their values.”
The long-term benefits of psilocybin are being explored.
“Some of the differences between short- and long-term outcomes were surprising, though it is hard to infer much due to the small sample size,” Pilecki said. “For example, of all the processes that were measured, we found increases in self-compassion at the six-month follow-up suggesting that psilocybin may lead to enduring changes in one’s relationship to themself.”
As with many psilocybin-related studies, the control group size was very limited, suggesting that more research is needed to determine the fungi’s efficacy in treating mental disorders.
“This was a small pilot study without a control group, so results must interpreted with caution,” Pilecki noted. “However, positive results suggest further research in this area is warranted.”
Author: mscannabiz.com
MScannaBIZ for all you Mississippi Cannabis News and Information.
You may like
-
Massachusetts regulators order single-lab testing to combat cannabis lab shopping
-
Cansortium completes merger with RIV Capital, plans to scale up in New York
-
The Daily Hit: December 19, 2024
-
Legal cannabis brands find their footing in New York
-
Oregon Cannabis: State of the State (2024) – Cannabis Business Executive
-
Marijuana activist leaders optimistic for progress in 2025
Business
Appeals court to hear case on psilocybin use by terminally ill
Published
6 months agoon
June 11, 2024
The Ninth Circuit will weigh whether “right-to-try” laws allow patients to access psychedelic substances.
The Ninth Circuit Court of Appeals is set to hear arguments in August in a closely watched case about whether terminally ill patients have the right to use the psychedelic drug psilocybin under federal and state “right-to-try” laws, Law360 reported.
The case, Advanced Integrative Medical Science Institute v. U.S. Drug Enforcement Administration, was brought by Dr. Sunil Aggarwal, a Seattle physician who’s seeking to provide psilocybin to his dying cancer patients to treat depression and anxiety.
Aggarwal and his clinic argue that laws aimed at allowing terminal patients to try experimental medications should permit the use of psilocybin in this context. The DEA and Justice Department counter that right-to-try statutes don’t override the federal prohibition on the substance.
Oral arguments in the case are scheduled for the morning of Aug. 19 in San Francisco, the Ninth Circuit announced Sunday.
The current appeal is part of a broader effort by Aggarwal to expand access to psilocybin for end-of-life care. The DEA has repeatedly rejected his proposals, arguing that providing the substance would be inconsistent with public health and safety and that Aggarwal must register as a researcher to obtain it.
Aggarwal sued the DEA in 2022, alleging its decisions were arbitrary and contradicted legal precedent allowing limited therapeutic use of other restricted drugs. The agency has insisted that Aggarwal hasn’t provided sufficient evidence and that it can’t fully assess his waiver request without more specifics.
In a separate case, the Ninth Circuit ordered the DEA to clarify its rationale for keeping psilocybin in Schedule I after rejecting a petition by Aggarwal to reclassify it.
Though currently illegal, psilocybin has received “breakthrough therapy” designation from the FDA twice and is now undergoing late-stage clinical trials. Any ruling by the Ninth Circuit in Aggarwal’s case could mean reverberations for its legal status and availability to patients.
Author: mscannabiz.com
MScannaBIZ for all you Mississippi Cannabis News and Information.
A newly published study from researchers at New York University found that individuals dealing with a stutter derived some benefit from substances such as psilocybin, the psychoactive compound in “magic mushrooms,” and LSD.
“Given the positive effects of psychedelics on conditions like anxiety and PTSD, which share symptoms with stuttering, we think that investigating the potential impact of psychedelics on stuttering can be a fruitful area of research,” said Eric S. Jackson, an associate professor of communicative sciences and disorders at NYU Steinhardt School of Culture, Education, and Human Development, and the lead author of the study.
The research, published this month in the Journal of Fluency Disorders, is the “first study to explore self-reported experiences of self-identified stutterers using classic psychedelics.”
“Stuttering poses challenges to social, occupational, and educational aspects of life. Traditional behavioral therapies can be helpful but effects are often limited. Pharmaceutical treatments have been explored, but there are no FDA-approved treatments for stuttering. Interest has grown in the potential use of classic psychedelics, including psilocybin and LSD, which have shown effectiveness in treating disorders with similar symptoms (e.g., anxiety, depression, PTSD). The potential effects of psychedelics on stuttering have not been explored,” Jackson and his team wrote in the study’s abstract.
Stuttering is “typically characterized by its symptoms—intermittent disruptions in speech,” they added.
“Stuttering, or the possibility of stuttering, also triggers anxiety, fear, and shame which significantly impact quality of life. Negative reactions of listeners, such as teasing or mocking exacerbate these feelings, complicating the individual’s ability to cope with and move forward in speech when stuttering occurs. The speech of stutterers is amenable to change in therapy, but such change is often not durable with relics of tension, struggle, and avoidance re-emerging,” the researchers said. “To achieve lasting changes, stutterers may benefit from redefining their relationship with stuttering, exploring concepts like openness and self-acceptance. There is a pressing need for innovative approaches that support overall well-being, reduce negative thoughts and emotions, and enhance ease of communication for stutterers.”
They “conducted a preliminary investigation of self-identified stutterers who report their experiences taking classic psychedelics on the online messaging forum, Reddit,” before performing a qualitative analysis on “114 publicly available posts, extracting meaningful units and assigning descriptor codes inductively.”
The researchers said that their search of Reddit “yielded 167 posts, with 14 excluded for lacking firsthand accounts (e.g., describing others’ experiences) and 39 for not discussing classic psychedelics (rather, they discussed ketamine or MDMA).
“The final sample comprised 114 posts from 104 Reddit distinct users, including multiple contributions from some users. Due to 12 users deleting their usernames, the exact number of unique users was estimated to be at least 92. Results reflective of individual percentages were based on 104,” they explained.
“We then deductively organized responses into an established framework of psychedelics which includes behavioral, emotional, cognitive, beliefbased, and social effects. These effects were subsequently grouped under organizing themes (positive, negative, neutral),” they wrote.
A majority of the users –– 74 percent –– ”reported positive overall short-term effects particularly related to behavioral and emotional change (e.g., reduced stuttering and anxiety), but negative (9.6%), mixed (positive and negative; 4.8%), and neutral overall experiences (11.6%) were also reported.”
“The results support the possibility that psychedelics my impact stuttering, but caution must be applied in their interpretation given the entirely uncontrolled research setting and potential adverse health effects of psychedelics as reported elsewhere. While these results do not encourage the use of psychedelics by stutterers, they suggest that future work could examine the impact of psychedelics on stuttering under supervised and in clinically controlled settings,” the researchers wrote.
They explained that the “results from a qualitative analysis of self-identified stutterers’ experiences of classic psychedelics, providing an initial investigation of the potential impact of psychedelics on stuttering from the perspective of stutterers.”
The most reported effect among Reddit users, the researchers said, “was reduced stuttering, with half of users reporting a reduction in their stuttering.”
“Users also reported reduced effort, ‘improved’ speech, and increased speech control while on psychedelics or shortly thereafter,” the researchers said.
“People who stutter are in need of more effective treatments to manage intermittent disruptions in speech communication and also provide relief from distress that accompanies their social experiences, such as anxiety, depression, and suicidal ideation,” they wrote in their conclusion. “To date, there are no FDA-approved pharmacotherapies to treat stuttering. Our study suggests that some users on the internet forum Reddit who self-identify as people who stutter have reported beneficial short-term outcomes.”
Jackson said that the “results support the possibility that psychedelics may impact stuttering, but caution must be applied in their interpretation given the entirely uncontrolled research setting and potential adverse health effects of psychedelics as reported elsewhere.”
“While these results do not encourage the use of psychedelics by stutterers, they suggest that future work could examine the impact of psychedelics on stuttering in randomized controlled clinical trials,” Jackson said.
Author: mscannabiz.com
MScannaBIZ for all you Mississippi Cannabis News and Information.
Assembly Bill 10375
New Assembly Bill in New York Seeks To Legalize Psilocybin Service Centers
Published
7 months agoon
May 24, 2024
New York legislation Assembly Bill 10375 was recently introduced by Assembly Health Committee Chair Amy Paulin and aims to legalize psilocybin service centers.
If passed, the A10375 would amend public law “in relation to promoting the health and well-being of the citizens of the state of New York by establishing a comprehensive framework supporting public health and safety through regulated adult use, support services, and cultivation of psilocybin-containing fungi,” the bill stated.
It would also require that the Department of Health (DoH) take charge of regulations, which involves cultivator licenses and approving psilocybin service center facilities. It would also create a “Regulated Psilocybin Advisory Board” made up of 13 members to study federal laws and policies regarding psilocybin, and offer advice and recommendations to the DoH. The purposes of the board would be to “develop a long-term strategic plan for ensuring that psilocybin services in the state will become and remain a safe, accessible and affordable therapeutic option, including in therapeutic and medical treatments, for all persons eighteen years of age and older for whom psilocybin services may be appropriate.”
Psilocybin business expenses would be tax deductible, and proceeds and fees would go back into the program to fund “administration and other costs relating to programs pursuant to this title, including but not limited to public education and risks of using psilocybin.”
Currently there are 58 conditions that would qualify for a patient to utilize the services of a psilocybin center, which ranges from glaucoma, HIV/AIDS, migraines, multiple sclerosis, post-traumatic stress disorder, sleep disorders, treatment resistant depression, and so much more. Additionally, patients with other conditions not included in the initial list can also be considered for psilocybin therapy if it “has been identified in a study published in a medical or scientific journal.” In order for a patient to receive a permit for psilocybin therapy, they must first receive a health screening and complete a permit course.
The bill wouldn’t legalize psilocybin, and consumption, cultivation, and sales would be prohibited. Violators would be hit with a $250 fine and a maximum of 15 days imprisonment.
As of May 21, the bill has been sent to the Assembly Health Committee, of which Paulin is the chair.
Other legislation involving psilocybin has led to promising progress. In February 2023, Assemblymember Pat Burke introduced Assembly Bill 03581, which would establish a psilocybin assisted therapy grant program and allow patients to engage in such treatments either in a licensed treatment center, or at home if the patient cannot travel. “This country is facing a mental health crisis,” Burke wrote on X last year. “I am looking at all options to alleviate the pain so many are feeling. Breakthrough medicines like psilocybin are showing tremendous benefit. I carry the bill to legalize psilocybin therapy. Let’s get it done!”
In February 2024, Burke introduced Assembly Bill 08349 which would create a psilocybin therapy pilot program for 10,000 veterans and first responders. “We’re in a mental health crisis, and so we need every tool that’s available to us,” Burke said.
Meanwhile, the state’s legal cannabis industry continues to develop. In mid-April, the New York Cannabis Control Board approved 101 adult-use cannabis licenses. “With the Cannabis Control Board’s issuance of 101 adult-use cannabis licenses, New York’s legal cannabis industry continues to make significant progress with over 400 licenses issued in 2024,” Gov. Kathy Hochul said. “Strengthening New York’s equitable cannabis industry and ensuring the hard-working small business owners operating in the legal market have the licenses to open are the best way to protect the integrity of sales in New York.”
As of late April, the state celebrated the opening of its 100th dispensary, called Big Gas, which opened through the help of the New York State Cannabis Investment Fund. “New York State continues to make progress on standing up a safe and legal cannabis industry for business owners, farmers and residents across the state,” said Hochul about the news. “Today marks a historic milestone in establishing a thriving and equitable industry in our state with the 100th brick-and-mortar store opening.”
The topic of psilocybin continues to influence more illuminating research studies. One such study which was published this month in the Journal of Psychoactive Drugs showed evidence that it won’t change a person’s belief as an atheist, agnostic, or believer in God. “These findings suggest that concerns that psychedelics could change metaphysical beliefs or result in ‘conversions’ across religious affiliations may be overestimated,” wrote researchers of their findings. They added that “concerns related to changes in non-naturalistic beliefs or religious affiliation may be exaggerated.”
Other recent studies include a dive into psilocybin as a meditation enhancement, show evidence that psilocybin isn’t associated with paranoia risk, and proves that natural psilocybin has more therapeutic benefits in comparison to synthesized psilocybin.
Another psilocybin treatment center recently opened up in Oregon, called Ashland Healing Center, which is also the first black-owned treatment center. Additionally, the Oregon Health Authority approved another psilocybin license to Kaya Holdings Inc., for a business called The Sacred Mushroom, which plans to open sometime in June.
Author: mscannabiz.com
MScannaBIZ for all you Mississippi Cannabis News and Information.
Massachusetts regulators order single-lab testing to combat cannabis lab shopping
Cansortium completes merger with RIV Capital, plans to scale up in New York
The Daily Hit: December 19, 2024
Legal cannabis brands find their footing in New York
Oregon Cannabis: State of the State (2024) – Cannabis Business Executive
Marijuana activist leaders optimistic for progress in 2025
cbdMD posts lower annual sales, mixed fourth quarter
Vireo nabs $75M through 120M new shares, goes on acquisition spree
The Daily Hit: December 18, 2024
Organigram eyes global cannabis growth after Motif deal
Farm Bill extension leaves hemp industry intact for now, including intoxicating products
Cannabis predictions for 2025: Low prices, high taxes, and hash
Bat Feces Used to Fertilize Cannabis Is Linked to 2 Deaths – Cannabis Business Executive
Cannabis Potency Testing Needs to Be Done the Right Way for Consumer Protection – Cannabis Business Executive
Charlie Fox opens largest northeast dispensary in Times Square
Massachusetts regulators advance social cannabis consumption rules
MediPharm Labs sells Ontario facility for C$5.5M as part of streamlining plan
2024’s weed award winners and where to buy them
The Daily Hit: December 17, 2024
Ohio marijuana market continues maturing with new rules
Weedmaps co-founders bid to take company private
Organigram tops estimates, expands international reach ahead of major deal
Michigan’s cannabis prices continue to free fall, spelling trouble for industry
Kentucky governor defends out-of-state dominance during medical cannabis licensing lottery
Mississippi city official pleads guilty to selling fake CBD products
Free delta-9 gummies from Bay Smokes
May 2024 Leafly HighLight: Pink Runtz strain
Connecticut Appoints The US’s First Cannabis Ombudsperson – Yes there is a pun in there and I’m Sure Erin Kirk Is Going To Hear It More Than Once!
People In This State Googled ‘Medical Marijuana’ The Most, Study Shows
5 best CBD creams of 2024 by Leafly
New Study Analyzes the Effects of THCV, CBD on Weight Loss
Alert: Department of Cannabis Control updates data dashboards with full data for 2023
Curaleaf Start Process Of Getting Their Claws Into The UK’s National Health System – With Former MP (Resigned Today 30/5/24) As The Front Man
Thailand: Pro-cannabis advocates rally ahead of the government’s plan to recriminalize the plant
Horn Lake denies cannabis dispensary request to allow sale of drug paraphernalia and Sunday sales | News
Press Release: May 9, STIIIZY and Healing Urban Barrios hosted an Expungement Clinic & Second Chance Resource Fair
Ohio legal cannabis buyer’s guide to 2024
Marijuana Rescheduling: Why Opponents Have No Idea What They Are Talking About
President Biden Announces Federal Government Will Reschedule Cannabis in ‘Monumental’ Announcement
Monitoring Weed’s Business Landscape
Majority of Texans Now Support Legalizing Pot for Adult Use
Medical Cannabis changes to take effect July 1
Benefits of Kratom: Uses, Effects And More
Planet 13 reports $6M loss in first quarter, preps for Florida expansion
Australia: Legalise Cannabis MP Sophia Moermond quits party over offshore wind farm opposition
Cannabis lab files appeal with Mississippi State Department of Health
DeSantis Likely To Veto Hemp Bill that Would Limit THC, Sources Say
Senator Cory Booker Visits Sacramento Cannabis Giant Amid Decriminalization Push
Trending
-
Mississippi Cannabis News8 months ago
Mississippi city official pleads guilty to selling fake CBD products
-
Bay Smokes6 months ago
Free delta-9 gummies from Bay Smokes
-
California8 months ago
May 2024 Leafly HighLight: Pink Runtz strain
-
Breaking News7 months ago
Connecticut Appoints The US’s First Cannabis Ombudsperson – Yes there is a pun in there and I’m Sure Erin Kirk Is Going To Hear It More Than Once!
-
Mississippi Cannabis News7 months ago
People In This State Googled ‘Medical Marijuana’ The Most, Study Shows
-
best list5 months ago
5 best CBD creams of 2024 by Leafly
-
cbd7 months ago
New Study Analyzes the Effects of THCV, CBD on Weight Loss
-
California Cannabis Updates7 months ago
Alert: Department of Cannabis Control updates data dashboards with full data for 2023