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Nothing Made Me Trip Harder Than My HIV Pills

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For people like me, the mild, somewhat psychedelic effects from cannabis are nothing compared to the side effects of pharmaceutical pills. When people suggest that medical cannabis shouldn’t be used because of its impact on our daily functions, or because it’s slightly psychedelic, it’s always good for a good laugh. I learned this through lived experience.

In 2011, I was diagnosed with HIV while living in Long Beach, California. A team of student nurses launched a project to pay people on the street $90 cash to get checked for HIV. One of my friends convinced me to join him and get tested. I was just there for support. After taking the test, when I saw the red plus sign on my card, I struggled to breathe. Growing up in the ‘90s and watching shows like KIDS taught me about the horrors of AIDS. I was completely ignorant about advances in medicine and the disease’s transformation into a chronic illness. 

In the past, getting diagnosed with HIV was virtually a death sentence, plain and simple. But today, HIV drugs that work much better and have fewer side effects are rolled out every few years. These have dramatically increased the average life expectancy of people with HIV over the past 25 years. For instance, one of the latest HIV drugs is a twice-yearly shot—you can essentially forget about medication for six months. There is also now PrEP for people without HIV, which is a pill that aims to block transmission, lowering the rate of infections.

Pills are mandatory for people with HIV in the U.S. to stop the spread of the disease. My doctor opted to hold off the pills for me for six months, due to the side effects. During this period, I took nothing but medical cannabis, and within that timeframe, I was able to control my viral load, which is the number of HIV copies in a blood sample.

Tripping on HIV Medication

My first pill, Atripla, contains efavirenz, a powerful hallucinogen with LSD-like effects. The way my doctor and Atripla commercials describe the effects talks about “abnormal dreams,” but in reality, they are nearly identical to an acid trip. Psychonauts have explored its recreational potential as a hallucinogen, but the hallucinations can be hit or miss. For me, I hallucinated about every three days—for two years—until my medication was updated. I took my pills in the evening, so I tripped during my sleep; however, I could remember all of the visuals when I woke up. The first night, my hallucination was the strongest, and I found myself in a technicolor carnival, and I saw family and friends participating in the trip.

In places like South Africa, efavirenz is the key ingredient of street drug blends like “whoonga” or “nyaope,” crushed up and smoked like crack. But it’s important to remember that for people in South Africa who have HIV, efavirenz is a life-saving drug.

Efavirenz can also cause a false-positive THC drug test. Efavirenz and THC share several similarities: Both closely affect peripheral neuropeptides, which signal inflammation and tissue repair, and both reduce oxytocin. And it’s ironic, because I got my California medical card days after my HIV diagnosis. “I finally have a legit reason for medical cannabis,” I told myself. I’d recommend taking both the pill and cannabis at the same time.

I was also prescribed steroids for HIV. Even the lowest dose of testosterone made me angry, and it was most evident while driving. Medical cannabis was especially effective at lowering anger while I was at home. I also smoke it before jogging every day. 

Efavirenz is the only HIV drug with weird or unwanted side effects. Other HIV drugs can keep you up at night.

“I first got an HIV diagnosis nine years ago,” says Doug Cahoon, a medical cannabis patient who was diagnosed in 2016. “Triumeq was the only option that didn’t have kidney side effects. And because I have kidney issues, so I went to Triumeq, but the side effect was insomnia.”

To get help falling asleep, Cahoon tried taking melatonin, sleeping pills—you name it.

“I tried all sorts of stuff,” he says. “And then I learned about cannabis. And I learned very quickly that I did sleep much better with an indica. I used it to sleep. I got on medical cannabis from a doctor and it was primarily for me to sleep. I started with gummies, I started experimenting with like tinctures and oils and different kinds of weed. I learned that indica was the calming strain within the college. So started doing that and I have not been worrying about it ever since.”

The physical dependence associated with some sleeping pills was another reason to opt for cannabis instead.

“It was like my mind wouldn’t calm down, and it was constant,” Cahoon says. “I’d lie down, my body’s tired, I haven’t slept for like two days, and just exhausted. I’d close my eyes and couldn’t go to sleep. I had my mind just about to shut up. I was taking Ambien to try to counterbalance it for a while, but I did not want to get hooked on that. Yeah. And so I moved to cannabis to try and see if that worked.” It did work, to an extent, and Cahoon takes cannabis at night to get some sleep.

Cannabis, Drugs, and HIV

Since the horrific AIDS epidemic was a key driving force in the original crusade to legalize medical cannabis—California’s Prop. 215, which took effect in 1996—many states list HIV or AIDS as one of the top qualifying conditions, and for good reason: Many people who advance to AIDS die of wasting syndrome—the loss of appetite—and an assortment of horrifying opportunistic infections that cause lesions and other scary side effects. And take a wild guess what can increase appetite? That’s where cannabis comes into the picture.

That’s precisely why early medical cannabis advocates like Dennis Peron and Mary Jane Rathbun, aka Brownie Mary, focused on HIV and AIDS as a reason to legalize medical cannabis. Back then, HIV drugs simply didn’t work. HIV is an entirely different beast compared to other viruses. It burrows into bone marrow and the brain, where it’s very difficult to deliver drugs. It hijacks T-cells, also called CD4 cells, and turns them into HIV factories. Scientists were finally able to control HIV with new medications. HIV needs specific enzymes in humans to make copies, and some modern drugs block the body from producing these enzymes. 

To be clear, what I went through is nothing at all like what people who were diagnosed with AIDS in the ‘80s or ‘90s. I didn’t watch my friends drop dead left and right. I was never afraid to leave the house due to opportunistic infections. I never had to be a guinea pig and take early drugs like AZT. I was never bedridden. Back then, people with full-blown AIDS took cannabis just to be able to eat and not die from wasting syndrome. I know because I’ve interviewed them.

The Trump administration is currently considering slashing life-saving drugs that will certainly lead to deaths for people who have HIV, perhaps 14 million. The administration is considering slashing and eventually phasing out the President’s Emergency Plan for AIDS Relief (PEPFAR)—installed by former president George W. Bush—to combat HIV/AIDS in developing countries. It’s pretty black and white that anyone who stops HIV medication will likely die, and the U.S. cannot let that happen. Without efavirenz and other drugs, I’d certainly be dead, perhaps around 2018 or so. Many people can say the same about medical cannabis.

Disclosure: This article is a personal account from a contributor and reflects their lived experience. It is not intended as medical advice. All medical decisions should be made in consultation with a licensed healthcare provider. The views expressed are those of the author and do not necessarily represent High Times. This story has been fact-checked for accuracy, and all medical claims are supported by linked sources.

Photo: Shutterstock



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Massachusetts Auditor Notes ‘Violations’ and ‘Mismanagement’ At Cannabis Control Commission

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Massachusetts Auditor Diana DiZoglio last week released an audit of the state’s Cannabis Control Commission (CCC), claiming to have uncovered violations and mismanagement issues at the commission, NBC Boston reports.

The audit found that officials “failed to take appropriate steps and institute procedures” to guarantee the administering of cannabis industry license extensions, and that a “lack of supervision and minimal accountability over licensing staff members” helped contribute to the breakdown.

“CCC’s mismanagement of prorated fees for license extensions resulted in procedural inequity, revenue loss, and noncompliance with state regulations.” — Excerpt from the audit summary

The commission said it has “been working closely with the State Auditor’s Office for almost a year and will review the report released today in furtherance of our shared commitment to government improvement. Over the course of the audit period and since, the Commission has hired key leaders, made progress to address many of the issues referenced, and begun to move forward in a constructive way.”

The report was released hours after the commission voted unanimously to reinstate the license of Assured Testing, a testing lab accused of failing to report thousands of contaminated cannabis samples, the report said. The commission issued penalties against the lab, including a $300,000 fine and two years of probation. Additionally, the lab — which has publicly disagreed with the findings but says it will honor the commission’s terms for reinstatement — will have to hire an independent auditor, an internal control manager, and a new interim CEO.

“We are eager to return to what we do best: delivering scientific, evidence-backed testing with industry-leading cannabis expertise,” Assured Testing said in a statement.



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Supreme Court Gives Marijuana Companies More Time To File Petition In Case Challenging Federal Prohibition

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The U.S. Supreme Court has granted a request to give marijuana companies suing the Justice Department in an effort to overturn federal prohibition two more months to file their petition with the justices.

Lawyers for the cannabis firms said the extension was needed due to the “significant and complex constitutional issues” that are being raised in the case, as well as the fact that state governments and other experts who plan to file support briefs need more time to “carefully craft their arguments.”

The prominent litigation firm Boies Schiller Flexner LLP that’s representing the companies—Canna Provisions, Gyasi Sellers, Wiseacre Farm and Verano Holdings—entered a request for a 60-day extension to submit its writ of certiorari last week. Justice Ketanji Brown Jackson approved the proposal on Friday, pushing back the current deadline of August 25 to October 24.

The companies’ request noted that counsel for the Office of the Solicitor General don’t oppose the extension.

The brief gave three reasons for the request: 1) the lead attorney on the case, David Boies, is “heavily engaged in previously scheduled matters” before other federal courts, 2) several experts who expressed interest in supporting their lawsuit with amicus briefs have said they need more time and 3) the case involves complex legal issues that require more in-depth consideration.

“This case presents significant and complex constitutional issues concerning both state-regulated marijuana specifically and the authority of Congress to regulate purely intrastate commerce generally,” the filing says. “The additional time will permit counsel to prepare a petition that appropriately addresses the questions of nationwide importance raised by this case.”

That includes “the question of whether [Gonzales v. Raich] was correctly decided,” it says, referencing a landmark 2005 Supreme Court ruling, wherein justices narrowly determined that the federal government could enforce prohibition against cannabis cultivation that took place wholly within California based on Congress’s authority to regulate interstate commerce.

With respect to future amicus briefs the applicants are expecting, they said “counsel have heard from law professors, non-profits, state governments, and others interested in submitting amicus briefs in these proceedings, and several of these potential amici have expressed concern about having sufficient time to prepare over the summer.”

“An extension will provide potential amici adequate time to consider the case and carefully craft their arguments,” the filing says.

This comes about three months after a U.S. appeals court rejected the arguments of the state-legal cannabis companies, one the latest blow to the high-profile lawsuit following a lower court’s dismissal of the claims. But it’s widely understood that the plaintiffs’ legal team has long intended the matter to end up before the nine justices.

“It’s fair to assume that we shall seek Supreme Court review,” attorney Jonathan Schiller told Marijuana Moment in June.

The latest filing concludes by saying respondents “will not suffer any prejudice from the requested extension,” and because “the First Circuit affirmed the dismissal of Applicants’ claims, a brief extension will not in any way alter the status quo of this case.”

While it remains to be seen whether the high court will ultimately take the case, one sign that at least some on court might be interested in the appeal is a 2021 statement from Justice Clarence Thomas, issued as the court denied review of a separate dispute involving a Colorado medical marijuana dispensary.

Thomas’s comments seemed to suggest that it’d be appropriate revisit Raich—a move that could largely upend federal prohibition.

The statement pointed to policy developments since the earlier case was decided, such as the hands-off enforcement approach taken by the Department of Justice as more states legalized cannabis and a congressional budget rider protecting state-legal medical marijuana programs.

“Whatever the merits of Raich when it was decided, federal policies of the past 16 years have greatly undermined its reasoning,” Thomas wrote, describing the government’s approach to cannabis enforcement as “a half-in, half-out regime that simultaneously tolerates and forbids local use of marijuana.”

“Though federal law still flatly forbids the intrastate possession, cultivation, or distribution of marijuana…the Government, post-Raich, has sent mixed signals on its views,” the justice continued, saying the situation “strains basic principles of federalism and conceals traps for the unwary.”

Once plaintiffs in the case at hand file their forthcoming petition for a writ of certiorari, it would need needs the votes of four justices to put the case before the Supreme Court.

The initial complaint, filed in U.S. District Court for the District of Massachusetts, argued that government’s ongoing prohibition on marijuana under the Controlled Substances Act (CSA) was unconstitutional because Congress in recent decades had “dropped any assumption that federal control of state-regulated marijuana is necessary.”

At oral argument on appeal late last year, Boies told judges that under the Constitution, Congress can only regulate commercial activity within a state—in this case, around marijuana—if the failure to regulate that in-state activity “would substantially interfere [with] or undermine legitimate congressional regulation of interstate commerce.”

Judges, however, said they were “unpersuaded,” ruling in last month’s opinion that “the CSA remains fully intact as to the regulation of the commercial activity involving marijuana for non-medical purposes, which is the activity in which the appellants, by their own account, are engaged.”

The district court, meanwhile, said in the case that while the there are “persuasive reasons for a reexamination” of the current scheduling of cannabis, its hands were effectively tied by past U.S. Supreme Court precedent in Raich.

Meanwhile, amid a series of legal challenges, the Trump administration recently asked the Supreme Court to take up a case on the federal government’s ban on users of marijuana and other illegal drugs from owning firearms and uphold the prohibition, saying it is consistent with the Second Amendment.

Separately at the federal level, a pending Biden-era recommendation to reschedule marijuana to the less restrictive Schedule III of the CSA is remains stalled.

The MAGA world is divided on how it wants President Donald Trump to come down on that proposal, with key right-wing influencers voicing conflicting positions on the issue after the president announced an imminent decision last week.

While Trump endorsed moving marijuana to Schedule III during last year’s presidential campaign—along with cannabis industry banking access and a Florida legalization ballot initiative that ultimately fell short—last week he merely said he is considering the issue, with a decision expected within weeks.

The overall bipartisanship of the issue, however, was also reflected in recent comments from one Democratic and one Republican member of Congress, who urged Trump to federally reschedule marijuana.

A new political committee that shares the same treasurer as Trump’s own super PAC is also pushing the president to follow through on rescheduling marijuana, releasing an ad that highlights his previous endorsement of the reform on the campaign trail.

Photo elements courtesy of rawpixel and Philip Steffan.

Marijuana Moment is made possible with support from readers. If you rely on our cannabis advocacy journalism to stay informed, please consider a monthly Patreon pledge.

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Canopy USA Appoints New Executive Team to Accelerate Growth

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[PRESS RELEASE] – BOULDER, Colo., Aug. 18, 2025 – Canopy USA LLC, a brand-driven organization strategically positioned across the fastest-growing states and highest potential segments of the U.S. cannabis market, announced the appointment of a new executive team responsible for driving the company’s next phase of expansion.

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Drawing on extensive industry experience, these leaders will steer Canopy USA forward through a shared vision to elevate the company’s brand portfolio, enhance day-to-day operations and execution, and advance growth initiatives across multiple state markets.

  • Casey Rashchief financial officer, will oversee centralized functions including finance, human resources and IT. Rash brings deep expertise in regulated industries and a strategic approach to driving organizational scale and efficiency.
  • Rebecca Kirkchief operating officer, will lead the company’s operations, innovation and legal teams. Known for building scalable systems and launching category-leading products, Kirk will play a critical role in driving Canopy USA’s performance across its value chain.
  • Kelly Floreschief business development officer, will be responsible for marketing, market expansion and product strategy. With a proven track record in cannabis commercialization, Flores will guide brand development and strategic growth initiatives in both existing and emerging state markets.

“These leadership appointments mark the start of a plan to capture growth in the U.S. cannabis market,” Canopy USA President Brooks Jorgensen said. “Within the best of each Acreage, Jetty and Wana, we’ve been aligning systems, teams and processes across markets to create a scalable, efficient organization. With our leadership team now in place, we’re moving forward with purpose.”

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Canopy USA’s platform is built to deliver consistent quality, innovative products and trusted brands to consumers and retail partners nationwide. By combining deep market expertise with a focus on execution, the company aims to set the standard for growth and leadership in the evolving U.S. cannabis industry.



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