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FDA asks veterinarians for input about CBD products for animals

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The Food and Drug Administration (FDA) is asking for comments from the public, particularly veterinarians, regarding the use of cannabis-derived products in animals, with an emphasis on cannabidiol (CBD) products. The FDA said it is interested in general trends associated with those products, including information about usage trends, quality standards, benefits of use, potential drug interactions, adverse events and safety problems, and toxicological concerns. Electronic or written comments must be submitted by April 16, 2025.

The FDA said that companies marketing CBD products for use in animals often make claims regarding a wide variety of diseases or conditions. Some products claim to enhance general wellness and promote longevity. These products are sold in many different formats, such as tinctures/oils, treats/chews, pellets for large animals, capsules, and sometimes as food toppers. Topical products infused with CBD, such as balms and shampoos, are also available for pets.

The notice added that the Center for Veterinary Medicine (CVM) is particularly interested in input from practicing veterinarians, whose expertise and experience can help inform the FDA regarding the use and effect of CDPs in animals.

Million dollar market

According to Grand View Research, the market was valued at approximately $248.39 million in 2023 and is projected to reach $1.72 billion by 2030, expanding at a compound annual growth rate (CAGR) of 32.47% from 2024 to 2030. Grand View also found that North America dominated the CBD pet market in 2023, accounting for over 40.22% of the global revenue. This research determined that Americans spend big bucks on pet care and have increasingly accepted CBD products for their pets.

Dogs are the biggest CBD patient population among pets and owners mostly use the products to treat joint pain. Grand View found that the joint pain market segment is expected to dominate the market, driven by the increasing prevalence of arthritis and other joint-related issues in pets.

Mordor Intelligence found that some of the top CBD pet product companies include Charlotte’s Web (OTC: CWBHF), Honest Paws, Pet Releaf, Canna-Pet and Green Roads.

Even Martha Stewart launched a CBD pet product line with Soft-Baked Chews and Oil Drops in 2021. These products were created with Canopy Growth Corporation (NASDAQ: CGC). “My dogs are not only my companions, but they are part of my family, and I prioritize their emotional and physical well-being as I do my own,” said Martha Stewart. “Just as CBD can support human wellness, it’s been shown to improve the quality of life for pets as well. With the help of the scientists and veterinarians at Canopy Animal Health, I’ve created CBD oil drops and savory soft-baked chews designed to support the health of dogs of all ages, sizes, and breeds in delicious gourmet flavors that your canines won’t be able to resist.”

FDA has not approved these products

Currently, there are no FDA-approved, conditionally approved, or indexed animal drugs that contain CBD. However, FDA has approved one cannabis-derived drug product for humans: EPIDIOLEX (cannabidiol), and three synthetic cannabis-related drug products: MARINOL (dronabinol), SYNDROS (dronabinol), and CESAMET (nabilone). It is worth noting that under the Animal Medicinal Drug Use Clarification Act of 1994 and its implementing regulations at 21 CFR part 530, veterinarians can lawfully prescribe approved human drugs for use in animals in an extralabel manner.

FDA said it has made the regulation of the CBD market a priority, including products marketed for animals. “While there is some limited published information about the use of CDPs in animals, significant data gaps exist surrounding many aspects of CBD and other CDPs in animals, and further research is necessary to assess the safety and effectiveness of these products. FDA is seeking a better understanding of what veterinarians are experiencing related to CDPs in their patients, such as general patterns of use, quality standards, benefits of use, potential drug interactions, adverse events and safety problems, and toxicological concerns,” said the notice.



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Nebraska medical cannabis regulations stall in legislative committee

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A Nebraska legislative committee voted 5-3 against advancing a bill designed to implement and regulate the state’s medical cannabis program, leaving legislators and advocates searching for alternative paths forward, according to the Nebraska Examiner.

The General Affairs Committee rejected Legislative Bill 677, sponsored by State Sen. Ben Hansen of Blair, during a Thursday vote where committee members declined to offer amendments to the legislation, the publication reported.

“I don’t want to shut all the doors right now, but some doors are closing, and they’re closing fast, and so we have to act,” Hansen told reporters after the vote, according to the Examiner.

Nebraska voters approved medical cannabis in November 2024, with residents legally permitted to possess up to 5 ounces with a healthcare practitioner’s recommendation since mid-December. However, the regulatory commission created by the ballot initiative lacks effective power and funding to regulate the industry.

Hansen described his legislation as “a must” for 2025 to prevent a “Wild West” scenario in the state’s cannabis market. The bill would have expanded regulatory structure through the Nebraska Medical Cannabis Commission and extended deadlines for regulations and licensing to allow more time for implementation, the Examiner noted.

Committee disagreements centered on proposed restrictions. A committee amendment would have prohibited smoking cannabis and the sale of flower or bud products while limiting qualified healthcare practitioners to physicians, osteopathic physicians, physician assistants or nurse practitioners who had treated patients for at least six months.

The amendment also would have limited qualifying conditions to 15 specific ailments including cancer, epilepsy, HIV/AIDS, and chronic pain lasting longer than six months.

State Sen. Bob Andersen of Sarpy County opposed allowing vaping due to concerns about youth drug use, while committee chair Rick Holdcroft suggested selling cannabis flower would be “a gateway toward recreational marijuana,” a claim Hansen “heavily disputed,” according to the Examiner.

Hansen now faces a difficult path forward, requiring at least 25 votes to pull the bill from committee and then needing 33 senators to advance it across three rounds of debate, regardless of filibuster attempts.

Crista Eggers, executive director of Nebraskans for Medical Marijuana, remained optimistic despite the setback.

“This will not be the end,” Eggers said, according to the outlet. “Giving up has never been an option. Being silenced has never been an option. It’s not over. It’s not done.”

The legislative impasse is further complicated by ongoing litigation. Former state senator John Kuehn has filed two lawsuits challenging the voter-approved provisions, with one appeal pending before the Nebraska Supreme Court. The state’s Attorney General is also trying to do something about the hemp question, akin to other states across the country.



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One of Las Vegas’ cannabis lounges closes its doors

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Nevada’s cannabis lounge experiment faces some expected growing pains, with one of just two state-licensed venues closing its doors after barely a year in business, according to the Las Vegas Weekly.

“The regulatory framework, compliance costs and product limitations just don’t support a sustainable business model,” said Thrive Cannabis managing partner Mitch Britten, who plans to convert the space into an event venue until regulations loosen up.

The closure leaves Planet 13’s Dazed Consumption Lounge as the only operational state-regulated cannabis lounge in Nevada. Dazed manager Blake Anderson estimates the venue attracts around 250 customers daily, primarily tourists. One other establishment, Sky High Lounge, has operated since 2019 on sovereign Las Vegas Paiute Tribe land exempt from state regulations.

Even with Nevada regulators conditionally approving 21 more lounge licenses, potential owners are struggling to meet the $200,000 liquid assets requirement – particularly social equity applicants from communities hit hardest by prohibition.

Recreational marijuana has been legal statewide since 2017, but public consumption remains prohibited. That’s created an obvious disconnect for the millions of tourists who visit Las Vegas annually but have nowhere legal to use the products they purchase. The state recorded roughly $829 million in taxable sales during the 2024 fiscal year.

“It always comes down to money, and it’s difficult to get a space if you can’t afford to buy a building. On top of that, getting insurance and finding a landowner who’s willing to lease to a cannabis business is a challenge in and of itself,” said Christopher LaPorte, whose consulting firm Reset Las Vegas helped launch Smoke and Mirrors, told Las Vegas Weekly.

Many think the key to future success lies in legislative changes that would allow lounges to integrate with food service and entertainment – playing to Las Vegas’s strengths as a hospitality innovator. In the meantime, the industry will continue to adapt and push forward.

“Things take time,” LaPorte said. “There’s a culture that we have to continue to embrace and a lot of education that we still have to do. But at the end of the day, tourists need a place to smoke, and that’s what these places are.”



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Psyence Group consolidates its shares

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Psyence Group Inc. (CSE: PSYG) told investors that it will be consolidating all of its issued and outstanding share capital on the basis of every 15 existing common shares into one new common share effective April 23, 2025 with a record date of April 23, 2025. As a result of the consolidation, the issued and outstanding shares will be reduced to approximately 9,387,695 on the effective date.

This is the second time a Psyence company has consolidated shares recently. In November, its Nasdaq-listed associate, Psyence Biomedical Ltd. (Nasdaq: PBM), implemented a 1-for-75 share consolidation as the psychedelics company worked to maintain its Nasdaq listing.

Psyence Group reported earnings in February when the company delivered a net loss of C$3 million and was reporting as a going concern. At the end of 2024, the company said it had not yet achieved profitable operations, has accumulated losses of C$48,982,320 since its inception.

Total assets at the end of 2024 were C$11,944,478 and comprised predominantly of: cash and cash equivalents of C$10,611,113, other receivables of C$159,808, investment in PsyLabs of C$1,071,981 and prepaids of C$68,243.

Still, the company is pushing ahead. Psyence told investors that it has historically secured financing through share issuances and convertible debentures, and it continues to explore funding opportunities to support its operations and strategic initiatives. “Based on these actions and
management’s expectations regarding future funding and operational developments, the company believes it will have sufficient resources to meet its obligations as they become due for at least the next twelve months,” it said in its last financial filing.

The company said it believes that the consolidation will position it with greater flexibility for the development of its business and the growth of the company.

 



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